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Abstract: Poster Presentations |

PREVALENCE OF ACUTE MYOCARDIAL INFARCTION IN PATIENTS WITH THROMBOTIC THROMBOCYTOPENIC PURPURA FREE TO VIEW

Kaushang A. Gandhi, MD*; Wilbert S. Aronow, MD; Parminder Singh, MD; Harit Desai, MD; Harshad Amin, MD; Mala Sharma, MD; Hoang M. Lai, MD
Author and Funding Information

New York Medical College, Valhalla, NY


Chest


Chest. 2009;136(4_MeetingAbstracts):109S-c-110S. doi:10.1378/chest.136.4_MeetingAbstracts.109S-c
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Abstract

PURPOSE:  To investigate the prevalence of acute myocardial infarction (AMI) in patients hospitalized for thrombotic thrombocytopenic purpura (TTP).

METHODS:  Thirty-eight patients (27 women and 11 men), mean age 44 years, were hospitalized with the diagnosis of TTP confirmed by a hematologist. We investigated the incidence of AMI which developed during hospitalization for TTP. AMI was diagnosed by new ECG changes, increased serum cardiac troponin I levels, and clinical symptomatology.

RESULTS:  Of the 38 patients, 8 (21%) developed new Q-wave AMI. Of these 8 patients with new AMI, 2 (25%) developed atrial fibrillation, 1 (13%) developed atrial flutter, and 1 (13%) developed supraventricular tachycardia.

CONCLUSION:  In conclusion, new Q-wave AMI developed in 21% of 38 patients hospitalized with a diagnosis of TTP. Supraventricular tachyarrhythmias developed in 50% of patients with TTP who developed AMI.

CLINICAL IMPLICATIONS:  Patients hospitalized for TTP have a high incidence of new AMI accompanied by supraventricular tachyarrhythmias and should be monitored for this.

DISCLOSURE:  Kaushang Gandhi, No Financial Disclosure Information; No Product/Research Disclosure Information

Wednesday, November 4, 2009

12:45 PM - 2:00 PM


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