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Abstract: Poster Presentations |

INDEPENDENT OF RACE, LOW EJECTION FRACTION DOCUMENTED DURING CARDIAC CATHETERIZATION IS ASSOCIATED WITH LONG-TERM ALL-CAUSE MORTALITY FREE TO VIEW

Sudhakar Sattur, MD*; Mohammad Reza Movahed, MD
Author and Funding Information

University of Arzona School of Medicine, Tucson, AZ


Chest


Chest. 2009;136(4_MeetingAbstracts):105S. doi:10.1378/chest.136.4_MeetingAbstracts.105S
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Abstract

PURPOSE:  : Decreased ejection fraction (EF) has been found to be strong predictor of mortality. However, the degree of different cut of point of ejection fractions with mortality over a very long period of over 10 years has not been studied well. Using a large data base of patients who underwent coronary angiography for clinical reasons, we evaluated any association between decreased ejection fraction and the severity of EF impairment with 10 year mortality stratified by race.

METHODS:  Using angiographic data of 1937 patients from 1993 to 1997 at a veteran administration hospital were studied. We evaluated different degree of decreased EF with all cause mortality using uni- and multivariate analysis.

RESULTS:  Total mortality was 22.9% of the cohort. Decreased EF was a strong predictor of death over a period of 10 years. (All cause mortality occurred in 21.6 % of patients with normal EF vs. 41.7 %, or 2.59, CI 2.06–3.26, p < 0.001). After adjustment for left main coronary artery disease, mitral regurgitation, 3 vessel coronary disease and clinical risk factors (diabetes, hypertension, hyperlipidemia and smoking), decreased EF remained independently associated with all cause mortality. This was independent on race (see figures).

CONCLUSION:  Decreased EF measured during coronary angiography remain a strong independent predictor of all cause mortality over a period of 10 years independent of race.

CLINICAL IMPLICATIONS:  Low EF documented during cardiac cathterization is an important indicator of poor prognosis.

DISCLOSURE:  Sudhakar Sattur, No Financial Disclosure Information; No Product/Research Disclosure Information

Wednesday, November 4, 2009

12:45 PM - 2:00 PM


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