To see rate of relapse among sputum smear +ve TB patients declared cured under RNTCP (DOTS).
We prospectively studied 203 Sputum smear for AFB +ve, pulm. TB patients declared cured in the 1st quarter of 2007.
In our study males were 137(67.49%) as compared to 64 (32.5%) females. 51.72% Patients (Pts) were in the 20–39 years age group. 113 (55.67%) patients were with initial sputum grading 3+. 60 (31.09%) patients gained weight between 4–6kgs. The relapses %age in both sexes was almost same i.e. 22 (16.06%) of male cases & 10 (15.15%) of females cases. Total 32/203 (15.76%) relapses were seen. The relapses %age was higher in Cat-II cases 7 (18.42%) of the 38 cases as compared to 25 (15.15%) of the 165 Cat-1 cases. 20 (9.85%) patients with higher grades of initial sputum smear (3+) had relapsed. Relapses were more among the male patients with initial sputum smear 3+. No relapses were seen among female patients with initial sputum smear 1+ & scanty+ respectively. Most of relapse among Cat-1 cases i.e. 17 (10.3%) were with initial sputum smear 3+. Whereas in Cat-II patients equal no. of relapses i.e. 3 (7.89%) were seen among patients with initial sputum smear 3+ and 2+ respectively. Most of Cat-1 patients relapsed with sputum smear 2+ i.e. 8 (4.85%). Most of Cat-II patients relapsed with sputum smear 3+. None of the Cat-II patients relapsed with sputum smear scanty+. Weight gain had impact on the relapse rates. Less than 4 kgs wt. gain pts. had most of the Relapses i.e. 21 (10.34%) in 2–4 Kgs wt. gain patients. None of cases had relapsed among those who gained wt. above 6 kgs. Majority of the relapses 10 (4.93%) were between 2–4 month's period of follow up. 64% of total relapses in cat-1 patients whereas 71.43% (5/7) of total relapse in Cat-II occurred within 1st 6 months of treatment completion.
Follow up to detect relapses earlier in patients with higher grades of initial sputum smear may help in timely retreatment.
Early detection & cure of Relapses.
Vinay Bhagat, No Financial Disclosure Information; No Product/Research Disclosure Information