Abstract: Poster Presentations |


Susan Zafarlotfi, PhD*; Hormoz Ashtyani, MD; Alexander Ackad, MD; Paula Ruiz-de Somocurcio, RN; Quadri N. Mohammed, MD
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Hackensack University Medical Center, Hackensack, NJ


Chest. 2009;136(4_MeetingAbstracts):66S. doi:10.1378/chest.136.4_MeetingAbstracts.66S-a
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PURPOSE:  According to National Commission on Sleep Disorders 40 million Americans are chronically ill with various sleep disorders and an additional 20 to 30 million experience intermittent sleep-related problems. Sleep Apnea (SA) is one of the most common sleep disorders and with perhaps the greatest medical and social impact on society in terms of morbidity and mortality. Sleep apnea is estimated to be about five times higher in kidney patients (Chronic Kidney Disease Stages 1–5) than in general population. Quality of life is affected in general in patients with Sleep Apnea and other sleep disorders which reduce productivity, lower cognitive performance, and increase likelihood of accidents, high morbidity and mortality risk. The goals of this study are to assess the efficacy of prolonged Nocturnal Hemodialysis in the treatment of Sleep Disorders (Periodic Limb Movement Syndrome and Obstructive Sleep Apnea) in patients with chronic kidney damage. The vascular pathogenic link between obstructive sleep apnea (OSA) and systemic hypertension may have peculiar implications in patients with chronic kidney disease.

METHODS:  Subjects are being recruited in an ongoing study from our existing patient population at hemodialysis unit. Results of overnight polysomnography were compared from prior to enrolment in Nocturnal hemodialysis and after 6 months.

RESULTS:  A total number of 6 patients are enrolled in an ongoing study. 3 patients completed the study procedures and their Apnea-Hypopnea index (5–11) along with periodic limb movement index (2–5) showed a reduction of more than 50% after 6 months of treatment with prolonged Nocturnal hemodialysis.

CONCLUSION:  Prolonged Nocturnal hemodialysis in patients with chronic kidney damage not only reduces sleep apnea and periodic limb movement syndrome but also improves quality of life improving social, mental and physical health of a patient.

CLINICAL IMPLICATIONS:  Patients with Chronic Kidney Disease (CKD) should be evaluated for sleep disorders. Prolonged Nocturnal Hemodialysis should be considered as a treatment option in patients with CKD and Obstructive Sleep Apnea and Periodic Limb movement Syndrome.

DISCLOSURE:  Susan Zafarlotfi, No Financial Disclosure Information; No Product/Research Disclosure Information

Tuesday, November 3, 2009

12:45 PM - 2:00 PM




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