Obstructive sleep apnea (OSA) and metabolic syndrome together constitutes “syndrome Z”. Our study was to compare prevalence of metabolic syndrome in north Indian patients with and without OSA.
We did a retrospective analysis of the patients referred to sleep centre of Government Medical College and Hospital, Chandigarh, India from Feb. 2006 to April 2009. We included 231 patients those comprised of 127 patients of OSA (AHI ≥ 5) and 104 patients without OSA (AHI < 5). All patients were undergone overnight polysomnography and evaluated for presence of metabolic syndrome on the basis of National Cholesterol education programme (NCEP) adult treatment panel III (ATP III) report (obesity, insulin resistance, hypertension, dyslipidemia included).
Seventy eight out of 127 (61.42%) patients of OSA and 20 out of 104 (19.23%) patients without OSA had metabolic syndrome ( OR, 6.68; 95% CI, 3.65 to 12.23; p < 0.0001).
Metabolic syndrome was significantly higher among patients of OSA as compared to patients without OSA among North Indian patients.
We need further multicentric studies to reconfirm our results on Indian population and polysomnography must be done in all patients of metabolic syndrome for detection of OSA.
Anup Singh, No Financial Disclosure Information; No Product/Research Disclosure Information