0
Abstract: Poster Presentations |

CLINICAL CORRELATION AND AGREEMENT BETWEEN THE CHEST CT SCAN AND CHEST X-RAY FINDINGS IN TUBERCULIN-POSITIVE CHILDREN: A PROSPECTIVE CROSS SECTIONAL STUDY FREE TO VIEW

Beverly D. Delacruz, MD*; Nerissa A. Deleon, MD; Milagros S. Bautista, MD; Fernando Ayuyao, MD; Teresita Deguia, MD
Author and Funding Information

Philippine Heart Center, Quezon City, Philippines


Chest


Chest. 2009;136(4_MeetingAbstracts):40S. doi:10.1378/chest.136.4_MeetingAbstracts.40S-a
Text Size: A A A
Published online

Abstract

PURPOSE:  To determine the correlation and agreement between of chest CT scan and chest x-ray findings among tuberculin skin positive children.

METHODS:  Ninety eight patient aged 6 months to 18 years old recruited were positive in tuberculin test with > 10 mm induratio. All received chest radiograph & chest CT scan as part of the routine TB work up. These plates were evaluated by 3 readers of the center blinded to the clinical diagnosis of the patient. An agreement among tuberculin skin test positive children with significant chest x-ray findings with the Chest CT scan results was made.

RESULTS:  A total of 98 children met the inclusion criteria(49% males and 51% females)The commonly affected age group was between 4–5 years old and between 9 and 11 years old (27% each).There was good agreement between reader 1 and reader 2 in the interpretation of normal chest findings (kappa=70%,p < .001) and between reader 2 and reader 3 (Kappa=62.7%,p < .001) but was poor with reader 1 and reader 3 (kappa= 53.7%, p < .001). In the interpretation of a normal chest-CT scan, three readers had higher agreement beyond chance (kappa=93.7%, 87.5%, 93.8%, all p-values < .05 , Among the specific lesions in the ct scan , there was excellent agreement among the three readers regarding the interpretation of a granuloma kappa=100%,p < .001); and peribronchial lymh nodes (kappa=100%, p < .001). There is low agreement between CT scan and chest radiography in discriminating normal from a abnormal findings for reader 1 (kappa=9.5%); reader 2 (kappa=6.2%); and reader 3 (kappa=10.1%). Abnormal CT scans did not significantly correlate with those of x-ray films across the three readers.(kappa=6.4%,p = .46).

CONCLUSION:  The correlation and agreement between chest ct scan and chest xray among tuberculin positive children was poor.Chest CT scan is more sensitive in confirming the diagnosis of Tuberculosis.

CLINICAL IMPLICATIONS:  Majority of pediatric TB cases are under or over diagnosed. The advent of using chest CT scan confirm and establish the diagnosis of TB disease in children.

DISCLOSURE:  Beverly Delacruz, No Financial Disclosure Information; No Product/Research Disclosure Information

Tuesday, November 3, 2009

12:45 PM - 2:00 PM


Figures

Tables

References

NOTE:
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).

Some tools below are only available to our subscribers or users with an online account.

Related Content

Customize your page view by dragging & repositioning the boxes below.

Find Similar Articles
CHEST Journal Articles
PubMed Articles
[Imaging and Laboratory Diagnostics for Tuberculosis]. Klin Monbl Augenheilkd 2016;233(5):587-93.
  • CHEST Journal
    Print ISSN: 0012-3692
    Online ISSN: 1931-3543