PURPOSE:To identify the incidence of idiopathic pulmonary fibrosis (IPF) in a population based cohort in the USA using the 2002 American Thoracic Society and European Respiratory Society (ATS/ERS) consensus statement.
METHODS:Retrospective cohort of all consecutive patients diagnosed with IPF (ATS/ERS criteria) between 1997 and 2005 in Olmstead County, MN. Incidence rates were calculated for those 50 years of age and older as the number of cases per 100,000 person years. The rates were directly age and sex-adjusted to the 2000 US white population.
RESULTS:52 cases (24 female and 28 men) were newly identified with IPF during the study period. Their mean age was 73 years, and 27% had biopsy proven disease. For the 9-year study period, the overall age and sex-adjusted incidence of IPF was 19.7/100,000 person-years (95% C.I. 14.4 to 25.1). The age and sex-specific incidence rates are presented in Table 1. From Poisson regression, the incidence of IPF was found to increased with older age (p<0.001).
CONCLUSION:The incidence of ATS/ERS consensus diagnosis of IPF in Olmsted County, MN is similar to prior death certificate-based reports. There have not been significant changes in the overall total incidence of IPF among Olmsted, MN residents after the 2002 ATS/ERS consensus statement.
DISCLOSURE:Evans Fernandez-Perez, No Financial Disclosure Information; No Product/Research Disclosure Information