PURPOSE: To determine the frequencies of various diagnostic methods in study population and compare the various positive proportions of these variables with each other.
METHODS: For each clinical suspect (who has combination of various at least 3 symptoms, including cough, fever, weight loss since more than 3 weeks duration) three sputa samples were collected and processed using the ZN staining technique. Frontal view CXR was taken. Mantoux test was performed.
RESULTS: The most common symptoms reported by our study subjects in order of decreasing frequency were cough (95%), sputum production (80%), anorexia (80%), Fever (70%), night sweats (70%) and Hemoptysis (65%). Among all (100%) clinical suspects, 86.7% were having one or more radiological findings on chest radiograph suggesting PTB, 40% of them were sputum smear positive for AFB and almost half (55%) of them were PPD reactors intradermally. In our study, the proportions of study subjects having clinical evidence along with positive radiological findings suggesting PTB was significantly higher than the proportion of the patients having clinical evidence and positive sputum for AFB on microscopy (p<0.0001) .Similarly the same group of study was significantly higher then proportion of the patients with clinical evidence and tuberculin reactors (p <0.001).However, the difference between the proportion of the patient with clinical evidence along with MT positive and patients with clinical evidence along with AFB positive on microscopy was not significant (p=0.159 chi square = 1.97).
CONCLUSION: In our setting, the clinical evidence supported with positive chest radiography consistent with PTB is useful tool to diagnose PTB.
CLINICAL IMPLICATIONS: It is easy,accessible and convenient method,available everywhere in Pakistan.
DISCLOSURE: Abdul Rahim Solangi, No Financial Disclosure Information; No Product/Research Disclosure Information