PURPOSE: Pulmonary function (PFT) and blood gas test (BGT) has been previously studied in Hispanic population at 2240 meters above sea level (ASL). Statistical estimation were done to know the physiologic behavior at less altitude. We don't know if this statistical approach is correct. In order to know the behavior of PFT and BGT at different levels of altitude, describe in Hispanic population normal values of these parameters and to compare with this statistical approach we studied this population.
METHODS: Design: Prospective. We studied 790 healthy subjects, at three different levels of altitude ASL.Group I: <999 m ASL, group II : 1000 a 1999 m ASL and group III >2000 m ASL ), We obtained demographics, BGT and PFT data. Statistical analysis: Data are expressed as mean ± standard deviation (M±SD); One way ANOVA with Bonferroni′s correction were gathered for differences between groups; Pearson correlation coefficient was used to express associations between BGT-altitude and PFT-altitude. Statistical significance was accepted with p<0.05.
RESULTS: We studied 790 healthy subjects: 407 men and 383 women. Age 28 ± 7 y.o. BGT and PFT at different altitude and statistical reference are showed in Table I . Correlations between altitude and BGT were: pH 0.651, Partial pressure of oxygen) (PO2, mmHg) -0.689, Partial pressure of dioxide carbon (PCO2, mmHg) -0.859 and PFT: Forced espiratory volume at the first second (FEV 1, Lts) -0.668, Forced vital capacity (FVC, Lts) -0.635, FEV1/FVC, Lts (ratio) 0.345, all of them with p<0.000.
CONCLUSION: BGT and PFT behaviors depend on the altitude. Our data were not similar with the statistical approach previously informed.
CLINICAL IMPLICATIONS: These values might be used as a reference for these levels of altitude in Hispanic healthy population.
DISCLOSURE: Briseyra Fong-Ponce, None.