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Abstract: Poster Presentations |

ABNORMALITY OF OSCILLOMETRIC RESISTANCE AND REACTANCE IS GREATER IN HISPANIC THAN ANGLO CHILDREN IN EL PASO, TX FREE TO VIEW

Michael Goldman, DSc*; Erika Meraz, MS; Homer Nazeran, PhD; Bill Diong, PhD
Author and Funding Information

University of Texas at El Paso, El Paso, TX


Chest


Chest. 2008;134(4_MeetingAbstracts):p140002. doi:10.1378/chest.134.4_MeetingAbstracts.p140002
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Abstract

PURPOSE: Hispanic patients (H) are reported to suffer more adverse respiratory consequences with asthma than Anglo patients (A), whereas urban living affects all persons at risk of asthma. No previous study has assessed physiological indices of respiratory dysfunction in H and A children in the same urban environment.

METHODS: Randomly selected El Paso children, ages 5–17 years, underwent oscillometry (IOS), to assess respiratory resistance (Rrs) and reactance (Xrs). IOS data were analyzed offline to exclude swallowing/airflow leak artifacts. Rrs and Xrs were compared with historical normal data in children of similar age to aid diagnostic assignment by an observer blinded to ethnicity/diagnosis of asthma/allergies. Diagnoses were: (a) normal, (b) possible peripheral airway impairment (PAI), (c) established PAI, or (d) asthmatic groups, based on IOS Rrs and Xrs. Equivalent electrical model analysis utilized an augmented RIC model, yielding estimates of central and peripheral airway resistance.

RESULTS: Children classified (a) or (b) did not differ in IOS/model analyses between H and A. Children classified (c) or (d) were significantly different, (unpaired t-test) independent of age/height: Rrs, Xrs and central airway resistance were greater in H in group (c); Rrs, Xrs, central and peripheral airway resistance were greater in H in group (d).

CONCLUSION: We conclude that in an urban environment with diminished air quality, H and A children whose Rrs and Xrs are normal for age and size do not differ. Among children whose IOS Rrs and Xrs are consistent with significant PAI, H children are more severely affected than A, with increased calculated large and small airway resistances.

CLINICAL IMPLICATIONS: Poor urban air quality may affect Hispanic children with PAI more severely than Anglo.

DISCLOSURE: Michael Goldman, No Financial Disclosure Information; No Product/Research Disclosure Information

Wednesday, October 29, 2008

1:00 PM - 2:15 PM


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