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Abstract: Poster Presentations |

ENDOBRONCHIAL ULTRASOUND-GUIDED TRANSBRONCHIAL BIOPSY USING A 3 4-MM THIN BRONCHOSCOPE FOR DIAGNOSIS OF PERIPHERAL PULMONARY LESIONS FREE TO VIEW

Masahide Oki, PhD*; Hideo Saka, MD; Chiyoe Kitagawa, PhD; Yoshihito Kogure, MD; Kouki Mori, MD; Shigehisa Kajikawa, MD
Author and Funding Information

Nagoya Medical Center, Nagoya, Japan


Chest


Chest. 2008;134(4_MeetingAbstracts):p97003. doi:10.1378/chest.134.4_MeetingAbstracts.p97003
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Abstract

PURPOSE:The aim of this study was to evaluate the diagnostic utility of endobronchial ultrasound (EBUS)-guided transbronchial biopsy (TBB) using a novel 3.4-mm thin bronchoscope and a 1.4-mm EBUS probe for peripheral pulmonary lesions.

METHODS:A total of 86 patients with suspected peripheral lesions were included in this prospective study. After informed consent was obtained, EBUS-TBBs were performed using a prototype 3.4-mm thin bronchoscope (XBF-3B260Y1; Olympus) and a 1.4-mm radial ultrasonic probe (XUM-S20–17R; Olympus) under fluoroscopic guidance. Peripheral lesions were defined as the lesions located beyond the segmental bronchi.

RESULTS:Twelve patients with endobronchial lesions within the segmental bronchi that were defined as central lesions and 3 patients who did not return to follow-up were excluded from this analysis. Thus, a total of 71 patients (45 men and 26 women; mean age, 67.2 years) with peripheral pulmonary lesions (mean size, 31.2 ± 12.7 mm; range, 8 to 70 mm) were included in the final analysis. The mean bronchus level reached with the thin bronchoscope was 4.6th generation bronchi. Diagnostic histologic specimen was obtained in 49 of 71 patients (69%: 52% for benign lesions and 80% for malignant lesions). A definitive diagnosis of malignancy for lesions ≥ 20 mm and lesions < 20 mm was made in 82% (31 of 38) and 67% (4 of 6), respectively. There were no major complications.

CONCLUSION:EBUS-TBB using a 3.4-mm thin bronchoscope and a 1.4-mm radial probe is accurate and safe for the diagnosis of peripheral pulmonary lesions.

CLINICAL IMPLICATIONS:This procedure may be a useful alternative to conventional bronchoscopy for examining peripheral pulmonary lesions.

DISCLOSURE:Masahide Oki, No Financial Disclosure Information; No Product/Research Disclosure Information

Wednesday, October 29, 2008

1:00 PM - 2:15 PM


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