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Abstract: Poster Presentations |

CLINICAL ASSESSMENT OF THE DIAGNOSTIC EFFICACY OF FLEXIBLE BRONCHOSCOPIC CRYOBIOPSY: A COMPARISON BETWEEN CRYOBIOPSY AND FORCEP BIOPSY FREE TO VIEW

Chulho Oak, MD*; Taewon Jang, MD; Mannhong Jung, MD
Author and Funding Information

Kosin University Gospel Hospital, Pusan, South Korea


Chest


Chest. 2008;134(4_MeetingAbstracts):p96002. doi:10.1378/chest.134.4_MeetingAbstracts.p96002
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Abstract

PURPOSE:The purpose of this study was to assess the diagnostic efficacy, tissue size and side effects between flexible bronchoscopic cryobiopsy and forcep biopsy in patients with lung cancer.

METHODS:from May 2007 to october 2007, 20 non-small cell lung cancer patients (squamous cell carcinoma 15 patients, adenocarcinoma 5 patients)with endobronchial lesion(nodular or polypoid) under bronchoscopy were enrolled. Firstly, the patients underwent routine flexible bronchoscpy with standard forcep biopsy. After then, bronchoscopic cryobiopsy was performed using a flexible cryoprobe(ERBE USA Inc.,Marietta, Ga.,USA). The cryoprobe was activated with a foot pedal until iceball appear (within 30 s), then to remove tissue from tumor, the probe was retracted after release of the foot pedal using probe-tissue adherence.

RESULTS:: A size of specimen in cryobiopsy was significantly larger compared to forcep biopsy (2.0±1.2mm, 6.0±3.0mm, respectively p=0.001). The diagnostic rate in forcep biopsy and cryobiopsy were 75%(15/20), 95%(19/20), respectively(p=0.06). No major complications occurred in both group.

CONCLUSION:Flexible bronchoscopic cryobiopsy was safe diagnostic method and may be helpful to get large tissue from endobronchial lesion.

CLINICAL IMPLICATIONS:tissue culture, anticancer drug susceptibility, prognosis.

DISCLOSURE:Chulho Oak, No Financial Disclosure Information; No Product/Research Disclosure Information

Wednesday, October 29, 2008

1:00 PM - 2:15 PM


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