PURPOSE:19–51% of inferior acute myocardial infarction(AMI) patients combine with right ventricular infarction(RVI). RVI is associated with a highly increased in-hospital mortality. Therefore, early diagnosis of RVI in inferior acute myocardial infarction is very important. This study was planned to investigate the usefulness of B-type natriuretic peptide(BNP) in the early diagnosis of RVI.
METHODS:The patients who were diagnosed as inferior AMI and primary coronary intervention done within 6 hours were selected for this study. The subject patients(n=100) had a significant luminal narrowing at right coronary artery, and no specific findings in left coronary artery on coronary angiograms. The patients were divided into group A for those who had a proximal lesion and RVI, group B with a proximal lesion but without RVI, and group C with a distal lesion.
RESULTS:Twenty eight of the 100 subject patients suffered from RVI. Among 72 patients who did not accompany with RVI, 26 (36%) had a significant stenosis in their proximal portion while 46 (64%) had a significant distal stenosis. The level of BNP was 298.8±138.5 pg/mL in group A (n=28), 83.2±53.6 pg/mL in group B (n=26), and 68.1±46.9 pg/mL in group C (n=46) respectively. BNP was increased when RVI was accompanied regardless of the site of the lesion.
CONCLUSION:BNP is a useful marker for diagnosis of combined RVI in case of inferior AMI.
CLINICAL IMPLICATIONS:BNP is a useful marker for diagnosis of combined RVI in case of inferior AMI.
DISCLOSURE:Hyeon Gook Lee, No Financial Disclosure Information; No Product/Research Disclosure Information