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Abstract: Poster Presentations |

DIABETICS WITH STROKE HAVE A HIGHER HEMOGLOBIN ALC LEVEL AND A HIGHER SERUM LOW-DENSITY LIPOPROTEIN CHOLESTEROL THAN DIABETICS WITHOUT STROKE FREE TO VIEW

Gautham Ravipati, MD*; Wilbert S. Aronow, MD; Sujata Kumbar, MD; Anil Kumar, MD; Ranee Rapera-Lleva, MD; Gwendoline Menga, MD; Melvin B. Weiss, MD; John A. McClung, MD
Author and Funding Information

New York Medical College, Valhalla, NY


Chest


Chest. 2008;134(4_MeetingAbstracts):p43001. doi:10.1378/chest.134.4_MeetingAbstracts.p43001
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Abstract

PURPOSE: We investigated risk factors for ischemic stroke in patients with diabetes mellitus.

METHODS: We investigated in 408 diabetics, mean age 66 years (47% women), with ischemic stroke and in 404 age-and sex-matched diabetics without ischemic stroke risk factors for stroke.

RESULTS: The prevalence of race, hypertension, smoking, obesity, prior stroke, atrial fibrillation, carotid arterial disease, and prosthetic valve was similar between diabetics with and without stroke. A hemoglobin A1c level <7.0% was present in 141 of 408 diabetics (35%) with ischemic stroke and in 221 of 404 diabetics (55%) without ischemic stroke (p<0.001). A serum low-density lipoprotein (LDL) cholesterol <100 mg/dl was present in 164 of 408 diabetics (40%) with ischemic stroke and in 269 of 404 diabetics (67%) without ischemic stroke (p<0.001). A serum LDL cholesterol <70 mg/dl was present in 34 of 408 diabetics (8%) with ischemic stroke and in 127 of 404 diabetics (31%) without ischemic stroke (p<0.001).

CONCLUSION: Diabetics with a hemoglobin A1c level of 7.0% or higher and a serum LDL cholesterol of 100 mg/dl or higher have a higher prevalence of ischemic stroke than diabetics with lower hemoglobin A1c and serum LDL cholesterol levels.

CLINICAL IMPLICATIONS: Patients with diabetes mellitus should have their hemoglobin A1c reduced to <7.0% and their serum LDL cholesterol reduced to <70 mg/dl.

DISCLOSURE: Gautham Ravipati, No Financial Disclosure Information; No Product/Research Disclosure Information

Tuesday, October 28, 2008

1:00 PM - 2:15 PM


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