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Abstract: Poster Presentations |

PATIENTS WITH INFECTIVE ENDOCARDITIS AND INCREASED CARDIAC TROPONIN I LEVELS HAVE A HIGHER INCIDENCE OF IN-HOSPITAL MORTALITY AND VALVE REPLACEMENT THAN THOSE WITH NORMAL CARDIAC TROPONIN I LEVELS FREE TO VIEW

Peter Tsenovoy, MD*; Wilbert S. Aronow, MD; Julie Joseph, MD; Magdaline S. Kopacz, MD
Author and Funding Information

New York Medical College, Valhalla, NY


Chest


Chest. 2008;134(4_MeetingAbstracts):p26002. doi:10.1378/chest.134.4_MeetingAbstracts.p26002
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Abstract

PURPOSE: To investigate the association of increased cardiac troponin I levels with in-hospital mortality and valve replacement in patients with infective endocarditis.

METHODS: The 62 patients included 36 men and 26 women, mean age 60 ± 9 years, with infective endocarditis diagnosed by the Duke criteria. All 62 patients had blood drawn for measurement of cardiac troponin I levels. A cardiac troponin I level >0.4 ng/ml was considered increased. All 62 patients underwent transesophageal echocardiography.Student's t tests were used to analyze continuous variables. Chi-square tests were used to analyze dichotomous variables.

RESULTS: Transesophageal echocardiography diagnosed valvular vegetations in 56 of the 62 patients (90%). Cardiac troponin I levels were increased in 35 of the 62 patients (57%). In-hospital mortality or valve replacement occurred in 18 of 35 patients (51%) with increased cardiac troponin I levels versus 4 of 27 patients (15%) with normal cardiac troponin I levels (p<0.005).

CONCLUSION: In conclusion, patients with infective endocarditis and increased cardiac troponin I levels have a higher incidence of in-hospital mortality or valve replacement than those with normal cardiac troponin I levels.

CLINICAL IMPLICATIONS: Patients with infective endocarditis and increased cardiac troponin I levels are at high risk for in-hospital mortality or valve replacement.

DISCLOSURE: Peter Tsenovoy, No Financial Disclosure Information; No Product/Research Disclosure Information

Tuesday, October 28, 2008

1:00 PM - 2:15 PM


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