Abstract: Poster Presentations |


Magnus Lofdahl, PhD*; Jenny Theorell-Haglow, RN; Inga Sif Olafsdottir, MD; Eva Lindberg, PhD; Christer Jansson, PhD
Author and Funding Information

Deptartment of Medical Scienses: Respiratory Medicine and Allergology, Uppsala, Sweden


Chest. 2008;134(4_MeetingAbstracts):p20002. doi:10.1378/chest.134.4_MeetingAbstracts.p20002
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PURPOSE: Patients with chronic obstructive pulmonary disease (COPD) do often report sleep disturbances. Relatively few studies have, however, investigated quality of sleep with objective measures in COPD. The aim of this study was to measure the quality of sleep in COPD patients by use of polysomnography, and compare this with assessments from control subjects.

METHODS: 100 patients with COPD and 100 age and sex-matched control subjects with normal pulmonary function were recruited. In all individuals, height and weight was measured. Subsequently, all participants underwent spirometry and ambulatory polysomnography. Acceptable sleep recordings were obtained from 98 COPD patients and 96 controls.

RESULTS: Characteristics of patients and control subjects are presented in table 1. The COPD patients had lower FEV1, oxygen saturation when awake (SaO2awake) and body mass index (BMI) than the control group. The results of the sleep recordings are presented in Table 2. Patients with COPD had significantly longer total sleep time (TST) and sleep latency (SL), a higher number of awakenings and lower oxygen saturation during sleep (SaO2 sleep) than the control group. No significant differences were found regarding sleep stage distribution. All differences except for TST remained statically significant after adjusting for age, sex and body mass index (BMI).

CONCLUSION: COPD patients have more problems falling asleep, more awakenings and lower oxygen saturation during sleep than age and sex matched subjects without COPD. No difference, however, was found regarding distribution of sleep stages.

CLINICAL IMPLICATIONS: Affected quality of sleep is a potential co-morbidity in COPD and shoud be taken in consideration when evaluating these patients. Sleep disturbances may contribute to the deteriorated quality of life associated with COPD. Quality of sleep is a potential goal of treatment in COPD.

DISCLOSURE: Magnus Lofdahl, No Financial Disclosure Information; No Product/Research Disclosure Information

Tuesday, October 28, 2008

1:00 PM - 2:15 PM




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