PURPOSE: Body mass index (BMI) is an independent prognostic factor in chronic obstructive pulmonary disease (COPD). Low BMI is a marker of poor prognosis in COPD. We explored distribution of BMI and its association with gravity, accompanied diseases and prognosis in a population of patients with COPD.
METHODS: We used data on 131 patients with COPD hospitalized in University Hospital of Pulmonary Diseases in Tirana, Albania, in a period of one year. The association between BMI, co morbidity and gravity of COPD was examined taking age, sex, smoking, and lung function into account. Data were analyzed using SPSS 12.0 for Windows. The results of regression analyses are given in terms of estimated relative risks (hazard ratios) with corresponding 95% confidence intervals.
RESULTS: The mean age was 65.9 ± 8.3 yr, men 66.09 ± 8.5 yr, women 64.3 ± 6.5 yr. Subjects with BMI < 20% with age < 60 yr made up 8.7% meanwhile older than 70 yr made up 14 .7%. About 25.5 % of patients with FEV1 < 1L had low BMI <20% meanwhile 7.5% of patients with FEV1 > 1L. According to CPOD staging 6.6% of patients in stage I-II had a BMI<20% comparing with 21.4% of patients in stage III-IV. Patients without co morbidity with BMI <20% made up1.01% of cases, comparing with 22.2% of patients with co morbidity.
CONCLUSION: BMI is an independent prognostic factor in COPD, with strong correlation between decreasing body mass and increasing of gravity in COPD and co morbidity. Further weight loss has not strong correlation with the rate of exacerbations.
CLINICAL IMPLICATIONS: Determination of BMI, diagnosis of co morbidities and its treatment have to be one of of main approaches in treatment of COPD patients.
DISCLOSURE: Perlat Kapisyzi, No Financial Disclosure Information; No Product/Research Disclosure Information