PURPOSE: It has long been recognized that left-sided heart failure patients have a high prevalence of central sleep apnea and Cheyne-Stokes respiration. The purpose of our study was to determine the occurrence of central sleep apnea and Cheyne-Stokes respiration in ambulatory patients with stable, optimally treated right-sided heart failure due to COPD.
METHODS: DESIGN: A case series study. SETTING: Referral sleep laboratory of Vallabhbhai Patel Chest Institute, Delhi University, Delhi, India. PATIENTS: 21 eligible patients with right-sided heart failure due to COPD were taken. Mean pulmonary artery pressure by two-dimensional echocardiography was greater than 25 mm Hg in all the patients. MEASUREMENTS: Whole night polysomnography (Medcare polygraph, Medcare Flaga, Reykjavik, Iceland) was done in all the subjects. Apnea-hypopnea index (AHI) was recorded for central apneas and hypopneas. Central sleep apnea was defined as AHI ≥ 5 per hour.
RESULTS: During whole night sleep studies, two out of 21 patients showed only one central sleep apnea each. None of the patients showed either Cheyne-Stokes respiration or significant hourly rate of central apnea and hypopnea i.e. apnea-hypopnea index (p < 0.0001).
CONCLUSION: The occurrence of central sleep apnea and Cheyne-Stokes respiration is negligible in ambulatory patients with stable, optimally treated right-sided heart failure due to COPD i.e. cor pulmonale.
CLINICAL IMPLICATIONS: There is no increased risk of central sleep apneas and Cheyne-Stokes respiration in patients of right sided heart failure due to COPD ( i.e. cor pulmonale ).
DISCLOSURE: Amit Bansal, No Financial Disclosure Information; No Product/Research Disclosure Information