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Abstract: Poster Presentations |

DO PATIENTS OF RIGHT-SIDED HEART FAILURE DUE TO CHRONIC OBSTRUCTIVE PULMONARY DISEASE HAVE INCREASED RISK OF DEVELOPING CENTRAL SLEEP APNEAS AND CHEYNE-STOKES RESPIRATION? FREE TO VIEW

Amit Bansal, MBBS, MD*; Sajal De, MBBS, MD; Kuldeep Patial; Sridhar Dwivedi; VK Vijayan, MD, FCCP
Author and Funding Information

Fortis Hospital, Mohali, Punjab, Chandigarh, India


Chest


Chest. 2007;132(4_MeetingAbstracts):651a. doi:10.1378/chest.132.4_MeetingAbstracts.651a
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Abstract

PURPOSE: It has long been recognized that left-sided heart failure patients have a high prevalence of central sleep apnea and Cheyne-Stokes respiration. The purpose of our study was to determine the occurrence of central sleep apnea and Cheyne-Stokes respiration in ambulatory patients with stable, optimally treated right-sided heart failure due to COPD.

METHODS: DESIGN: A case series study. SETTING: Referral sleep laboratory of Vallabhbhai Patel Chest Institute, Delhi University, Delhi, India. PATIENTS: 21 eligible patients with right-sided heart failure due to COPD were taken. Mean pulmonary artery pressure by two-dimensional echocardiography was greater than 25 mm Hg in all the patients. MEASUREMENTS: Whole night polysomnography (Medcare polygraph, Medcare Flaga, Reykjavik, Iceland) was done in all the subjects. Apnea-hypopnea index (AHI) was recorded for central apneas and hypopneas. Central sleep apnea was defined as AHI ≥ 5 per hour.

RESULTS: During whole night sleep studies, two out of 21 patients showed only one central sleep apnea each. None of the patients showed either Cheyne-Stokes respiration or significant hourly rate of central apnea and hypopnea i.e. apnea-hypopnea index (p < 0.0001).

CONCLUSION: The occurrence of central sleep apnea and Cheyne-Stokes respiration is negligible in ambulatory patients with stable, optimally treated right-sided heart failure due to COPD i.e. cor pulmonale.

CLINICAL IMPLICATIONS: There is no increased risk of central sleep apneas and Cheyne-Stokes respiration in patients of right sided heart failure due to COPD ( i.e. cor pulmonale ).

DISCLOSURE: Amit Bansal, No Financial Disclosure Information; No Product/Research Disclosure Information

Wednesday, October 24, 2007

12:30 PM - 2:00 PM


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