Abstract: Poster Presentations |


Ramesh Babu Kesavan, MD*; Tarik Haddad, MD; William Lunn, MD; Gnananandh Jayaraman, MD; Sivagini Ganesh, MD; Mathias Loebe, MD; Charlie Lan, DO; Rajesh Shetty, MD; Carmen Murray, RN; Harish Seethamraju, MD
Author and Funding Information

Baylor College of Medicine, Houston, TX


Chest. 2007;132(4_MeetingAbstracts):595b. doi:10.1378/chest.132.4_MeetingAbstracts.595b
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PURPOSE: To describe an acute progressive obliteration of lobar bronchus in lung transplantation(LT)- Vanishing Bronchus Syndrome(VBS).

METHODS: Prospective analysis of 59 patients who had undergone lung transplantation between the period of 2004 and 2006 was done. The following data was collected: Demographics, ischemic time, cardio-pulmonary bypass time, duration of mechanical ventilation, type of airway complication, pulmonary function test, chest X-ray, bronchoscopy findings, therapeutic intervention and rejection episodes. Patients with VBS and other airway complication(AC) were compared with patients without AC.

RESULTS: There were 52 patients who underwent double lung transplant and 7 single lung transplant. 18 of the 59 patients(30%) had AC. In the group with AC , 16 patients had luminal narrowing at the level of the anastamosis, and 3 patients had VBS. All the patients with VBS were in New York Heart Association(NYHA) Class 4 at presentation. Two patients with VBS had to undergo lobectomy and 1 patient underwent early sequential balloon dilatation with resultant patency of the airway and subsequent improvement in lung function.

CONCLUSION: Vanishing Bronchus Syndrome is a unique airway complication of Lung Transplantation. It is associated with acute worsening of pulmonary function. It is probably a result of aberrant airway healing in the back drop of an ischemic airway following Lung Transplantation.

CLINICAL IMPLICATIONS: Vanishing Bronchus Syndrome can result in acute worsening of pulmonary function and collapse of the involved lobe, which can be salvaged by early sequential dilatation of the bronchus.

DISCLOSURE: Ramesh Babu Kesavan, None.

Wednesday, October 24, 2007

12:30 PM - 2:00 PM




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