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Abstract: Poster Presentations |

LONG-TERM OUTCOME OF DRUG ELUTING STENTS COMPARED TO BARE METAL STENTS FREE TO VIEW

Darpan Bansal, MD; Raghu Muppidi, MD*; Jawahar L. Mehta, MD, PhD; Rajesh Sachdeva, MD
Author and Funding Information

University of Arkansas for Medical Sciences, Little Rock, AR


Chest


Chest. 2007;132(4_MeetingAbstracts):546. doi:10.1378/chest.132.4_MeetingAbstracts.546
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Abstract

PURPOSE: Long term safety of drug eluting stents (DES) is controversial. There is growing concern regarding late stent thrombosis, and associated myocardial infarction and mortality with DES. The objective of the study was to determine the long term outcome of DES and its comparison with bare metal stents (BMS).

METHODS: Study cohort was formed by all patients who had percutaneous intervention (PCI) done from January 2003 to August 2004 at our institution. A review of their medical records was done to obtain data regarding cardiac risk factors, medications at discharge, angiographic details and outcomes including death, target lesion revascularization (TLR), stent thrombosis and major adverse cardiac event (MACE).

RESULTS: A total of 465 interventions using stents were done in patients who were followed up for a mean duration of 36 ± 5 months. Cardiac risk factors and medications at discharge were similar in patients with DES and BMS (Table 1). There were more smokers in the group that received DES. Vessels implanted with DES had a smaller mean diameter compared to BMS (2.9 mm vs. 3.2, p=0.001) and had longer lesions (mean length 19 mm vs. 15 mm, =0.001).The long term outcome was similar between the two groups (Table 2).

CONCLUSION: Over 3 years of follow up, DES had similar rate of death, TLR, stent thrombosis, and MACE as did patients with BMS despite smaller coronary diameter and longer length.

CLINICAL IMPLICATIONS: This study provides data about the long term outcomes and safety of DES in the “real world” setting.

DISCLOSURE: Raghu Muppidi, No Financial Disclosure Information; No Product/Research Disclosure Information

Wednesday, October 24, 2007

12:30 PM - 2:00 PM


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