PURPOSE: To investigate the association between aortic valve calcium (AVC) and mitral annular calcium (MAC) diagnosed by 2-dimensional echocardiography and a coronary artery calcium (CAC) score diagnosed by cardiac computed tomography (CT).
METHODS: We investigated in 138 patients (76 women and 62 men), mean age 64± 8 years, seen in a cardiology private practice at New York Medical College the association between AVC and MAC diagnosed by 2-dimensional echocardiography and the CAC score diagnosed by cardiac CT. A CAC score of 1–100 was considered mild CAC. A CAC score of 101–400 was considered moderate CAC. A CAC score of >400 was considered severe CAC. AVC and MAC were diagnosed as mild, moderate, or severe.Calcium scoring was performed as a component of a complete cardiac CT study that included 64 slice coronary CT angiography, or as a stand alone procedure in patients referred for calcium scoring alone. Calcium scoring was performed by one of two cardiologists experienced in cardiac CT, employing a TeraRecon Aquarius workstation.
RESULTS: AVC was present in 25 of 57 patients (44%) with moderate or severe CAC and in 15 of 81 patients (19%) with 0 or mild CAC (p <0.001). Moderate or severe AVC was present in 9 of 57 patients (16%) with moderate or severe CAC and in 2 of 81 patients (2%) with 0 or mild CAC (p <0.005). MAC was present in 18 of 57 patients (32%) with moderate or severe CAC and in 7 of 81 patients (9%) with 0 or mild CAC (p <0.001). Moderate or severe MAC was present in 8 of 57 patients (14%) with moderate or severe CAC and in 2 of 81 patients (2%) with 0 or mild CAC (p <0.001).
CONCLUSION: patients with AVC or with MAC have a significantly higher prevalence of a moderate or severe CAC score than patients without AVC or MAC (p<0.001).
CLINICAL IMPLICATIONS: The presence of AVC or MAC should alert the physician to the possible presence of coronary artery disease.
DISCLOSURE: Hoang Li, No Financial Disclosure Information; No Product/Research Disclosure Information