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Abstract: Poster Presentations |

PREVALENCE OF OBSTRUCTIVE CORONARY ARTERY DISEASE IN PATIENTS WITH AND WITHOUT PRIOR STROKE UNDERGOING CORONARY ANGIOGRAPHY FOR SUSPECTED CORONARY ARTERY DISEASE FREE TO VIEW

Rasham Sandhu, MD*; Wilbert S. Aronow, MD, FCCP; Rishi Sukhija, MD; Archana Rachdev, MD
Author and Funding Information

New York Medical College, Valhalla, NY


Chest


Chest. 2007;132(4_MeetingAbstracts):544b. doi:10.1378/chest.132.4_MeetingAbstracts.544b
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Abstract

PURPOSE: To investigate in patients with prior stroke and in a control group of patients undergoing coronary angiography the prevalence and severity of obstructive coronary artery disease (CAD).

METHODS: The patients included 64 men and 38 women, mean age 71 ± 9 years, with prior stroke and in 102 age-matched and gender-matched patients with similar coronary risk factors without prior stroke who had coronary angiography for chest pain the prevalence and severity of obstructive CAD. All 102 patients with prior stroke had cerebral infarction documented by computer tomographic brain scans. Obstructive CAD was diagnosed if the patient had >50% narrowing of at least 1 coronary artery. Student's t tests were used to analyze continuous variables. Chi-square tests were used to analyze dichotomous variables.

RESULTS: Obstructive CAD was present in 100 of 102 patients (98%) with prior stroke and in 84 of 102 patients (82%) without prior stroke (p<0.001). Obstructive 3-vessel CAD was present in 56 of 102 patients (55%) with prior stroke and in 35 of 102 patients (34%) without prior stroke (p<0.005). Obstructive 2-vessel CAD was present in 23 of 102 patients (23%) with prior stroke and in 21 of 102 patients (21%) without prior stroke (p not significant). Obstructive 1-vessel CAD was present in 21 of 102 patients (21%) with prior stroke and in 28 of 102 patients (28%) without prior stroke (p not significant).

CONCLUSION: Patients with prior stroke have a significantly higher prevalence of obstructive CAD and of obstructive 3-vessel CAD than age-matched and gender-matched patients with similar coronary risk factors without prior stroke undergoing coronary angiography for chest pain.

CLINICAL IMPLICATIONS: Patients with prior stroke should have intensive treatment of modifiable coronary risk factors.

DISCLOSURE: Rasham Sandhu, No Financial Disclosure Information; No Product/Research Disclosure Information

Wednesday, October 24, 2007

12:30 PM - 2:00 PM


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