PURPOSE: Adequacy of cellular recovered from small needle aspiration is the point of question among pathologist and physician in the diagnosis of mediastinal mass. Many centers recommend fine needle aspiration biopsy for cytology as an adequate procedure in this situation. This study is aimed to find the value of cytology and histology examination in diagnosis of a mediastinal mass.
METHODS: The study was done by prospective collected data of patients who were consulted for needle aspiration biopsies of their mediastinal mass since 1999 to 2006 at the Respiratory Diagnostic Unit,Division of Respiratory disease and Tuberculosis,Faculty of Medicine Siriraj Hospital.The protocol in evaluating mediastinal mass was to obtain both cytologic slides and tissue for histology from lesions in mediastinum by ultrasonic guidance when they were possible.
RESULTS: During 1999 to 2006,there were 35 patients who had mediastinal masses referred for needle aspiration procedures.Their mean age and standard deviation were 42.37+/−16.97 year-old.Among these patients,22 were male and 13 were women.The mean age of male patients were 40.47+/−17.17 years and 45.5+/−16.79year-old for the female.The histology could make diagnosis in significant higher number of patients as compared to cytology(88.57% compared to 40%).There were statistically different higher diagnostic rate of histology than cytology in both carcinomatous group and non-carcinomatous group.The complication were mild.
CONCLUSION: The histology was more likely to make diagnosis of mediastinal mass than cytology. These benefits were in both carcinomatous and non-carcinomatous groups.
CLINICAL IMPLICATIONS: In mediastinal mass which many etiologic cell of origin cannot be diagnosed accurately by retrieved cytological cell,the fine needle aspiration for histology section is recommended as an initial investigation methods with out loss of time for cytological aspiration.
DISCLOSURE: Jamsak Tscheikuna, No Financial Disclosure Information; No Product/Research Disclosure Information