Abstract: Slide Presentations |


Li-Ying Wang, PhD*; Chien-Ling Su, MS; Ling-Ling Chiang, MS; Ying-Tai Wu, PhD; Huey-Dong Wu, MD
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School and Graduate Institute of Physical Therapy, National Taiwan Univeristy, Taipei, Taiwan ROC


Chest. 2007;132(4_MeetingAbstracts):472b. doi:10.1378/chest.132.4_MeetingAbstracts.472b
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PURPOSE: We have previously shown that a 6-week physical training program improves limb muscle strength, ventilator-free time, and functional outcomes in patients requiring prolonged mechanical ventilation (PMV). The aim of the present study was to examine the effects of this program after 1 year of follow-up.

METHODS: From January 2003 through September 2004, 39 patients with PMV were enrolled. Subjects were assigned to either a treatment group (n=20) receiving physical training 5 days a week for 6 weeks or a control group (n=19) receiving standard care. Baseline characteristics were similar between the groups. The outcome measures at 1 year were the mortality, weaning outcome, disposition, the functional status assessed by the Functional Independence Measure (FIM), and the quality of life measured by 12-item short-form (SF-12) Health Survey.

RESULTS: The overall cumulative probabilities of death were 25% and 70% at 1 year for patients in the treatment and control group, respectively. One patient and 4 patients were weaned from the ventilator and 1 and 5 patients were living at home at 1 year follow-up in the treatment and control group, respectively. No significant differences in the SF-12 physical component score between the 2 groups were noted, and the SF-12 mental component score were significantly higher in the treatment group at 1 year follow-up. The treatment group scored significantly higher, compared with the control patients, on the total (78 vs. 31, respectively, p<0.05) and all subscale FIM scores at 1 year follow-up.

CONCLUSION: This preliminary report demonstrates that a 6-week physical training program is effective in improving long-term outcome, i.e., functional status, overall survival, and health-related quality of life in patients with PMV.

CLINICAL IMPLICATIONS: Early referral for physical training in appropriate cases required prolonged mechanical ventilation might benefit overall long-term outcome.

DISCLOSURE: Li-Ying Wang, No Financial Disclosure Information; No Product/Research Disclosure Information

Tuesday, October 23, 2007

12:30 PM - 2:00 PM




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