PURPOSE: To identify the magnitude & impact of chronic cough on the QOL of our local urban setting at a tertiary care level.
METHODS: Medical records of 350 patients with chronic dry cough of more than 8 weeks were reviewed over the last seven years with special emphasis ona)Sleep disturbance (b)Cough related urinary stress incontinence in women (c)Cough syncope (d)interference with routine work schedule at office or home(e) interference with routine conversation (f) development of hernia –inguinal, incisional or anterior abdominal wall(g) Cough associated choking sensation while eating. b)Diagnosis of cough variant asthma was based on chronic cough without wheezing or dyspnoea & symptomatic response to inhaled Beta-2 agonist(Salbutamol) 87 subjects (25%) were current smokers and all smokers were males; 35 patients(10%) were ex-smokers.
RESULTS: There were 350 patients with cough variant asthma. Mean age 52.4 yrs + 2.6 SD; 210 were females (60%) ; 245 subjects (70%) had nocturnal or early morning sleep disturbance >than 3 times in a week due to cough; out of 210 female subjects 55% (n=115) had urinary stress incontinence which often prevented them from socializing; cough syncope was reported more in men than women and was observed in 175 patients (50%) half of these subjects were initially evaluated by neurologist for syncope. Interference with routine schedule of work at office/home in 122 subjects (n=35%) ; interference with routine conversation reported in 98 subjects (n=28%) cough related choking sensation while eating was reported in 86 subjects (n=25%) and was more in younger than older subjects; development of hernia due to chronic cough was seen in 18% of patients –mostly inguinal or incisional hernia in a previous anterior abdominal incisional scar.
CONCLUSION: Significant impairment of QOL due to chronic cough was observed in the cohort studied where majority of patients had sleep disturbance followed by urinary stress incontinence&cough syncope.
CLINICAL IMPLICATIONS: Chronic cough has a significant impact on the QOL which is often neglected by physicians and patients.
DISCLOSURE: Ajit Vigg, None.