Various pulmonary function tests have been used to identify potential candidates for lung resection and to predict morbidity and mortality rates after surgery. In this study, we investigated the use of quantitative breath sound measurements in conjunction with FEV1 to predict postoperative (PPO) lung function in patients who were candidates for lung resection surgery.
Ten candidates for lung resection (6 males and 4 females) were prospectively studied with Vibration Response Imaging (VRI)quantitative lung sound recordings and with perfusion lung scintigraphy and pulmonary function tests to predict PPO.
Average prediction by VRI for post pneumonectomy FEV1 (n = 8) was 1.54 ± 0.37 liters compared to 1.47 ± 0.34 for perfusion predictions. Actual FEV1 values in the patients who underwent surgery (lobectomy) and postoperative lung function testing (n = 4) were 69 ± 4% and 1.56 ± 0.13L compared to 67 ± 9% and 1.54 ± 0.26 for VRI and 67 ± 9% and 1.63 ± 0.26 for perfusion scintigraphy PPO values.
Although the sample size was small, VRI quantitative breath sound measurements showed similar results to those predicted by perfusion and to actual post-operative lung function.
VRI recording is a simple procedure that shows its potential as an alternative method for preoperative evaluation of lung resection candidates in settings where perfusion scanning is not readily available or cannot be tolerated by the patient.
Viliam Meissner, No Financial Disclosure Information; No Product/Research Disclosure Information