0
Abstract: Poster Presentations |

THE EFFICACY OF EBUS-TBNA ON THE DIAGNOSIS OF NODAL RECURRENCE AFTER SURGERY IN PATIENTS WITH LUNG CANCER FREE TO VIEW

Yuichi Sakairi, MD*; Takahiro Nakajima, MD; Yukiko Matsui, MD; Toshihiko Iizasa, MD; Kazuhiro Yasufuku, MD; Ichiro Yoshino, MD; Hideki Kimura, MD
Author and Funding Information

Chiba Cancer Center Hospital, Chiba-City, Japan


Chest


Chest. 2009;136(4_MeetingAbstracts):138S. doi:10.1378/chest.136.4_MeetingAbstracts.138S
Text Size: A A A
Published online

Abstract

PURPOSE:  Post-operative lymph node recurrence is defined through radiological examinations or serum tumor markers, since biopsy is often a challenge in post-operative patients with lung cancer. We have previously reported utility of EBUS-TBNA (endobronchial ultrasound-guided transbronchial needle aspiration) as a safe and minimally invasive diagnostic procedure for the evaluation of para-bronchial lesion. Through this study, we investigated the efficacy of EBUS-TBNA for detection of regional lymph node recurrence in post-operative patients.

METHODS:  A retrospective chart review of patients who underwent EBUS-TBNA for lymph node staging of lung cancer at Chiba Cancer Center from April 2008 to April 2009 was performed. 228 patients underwent EBUS-TBNA, out of which 15 patients were examined for the evaluation of lymph node recurrence. We analyzed the background, EBUS-TBNA result and the clinical outcome based on the EBUS-TBNA results in these cases.

RESULTS:  There were 12 men and 3 women (mean age 68 years). Histological diagnoses were 7 adenocarcinoma, 6 squamous cell carcinoma, 1 large cell carcinoma and 1 undefined. Initial staging classification was stage I (9 cases), II (1 case) and III (5 cases). All cases showed mediastinal lymphadenopathy on CT scan and a lung lesion was detected in 6 cases. Seven out of 9 patients showed abnormal studies on positron emission tomography scan. The mean number of involved nodal stations was 2.3 per patient, in which aspiration biopsy was performed in 1.9 stations.EBUS-TBNA revealed malignancy in 7 patients, of which 6 patients were determined as recurrent disease, however one was defined as second primary cancer based on histological type. In 8 patients that were defined as non-cancerous nodes, 4 were subjected to further examinations or to treatments for other lesions, and 4 were subjected to routine follow-up with disease-free condition.

CONCLUSION:  EBUS-TBNA is useful for the evaluation of post-operative nodal status in patients with lung cancer with a very high yield.

CLINICAL IMPLICATIONS:  EBUS-TBNA enables accurate diagnosis of mediastinal lymph node recurrence and leads to appropriate clinical decision during post-operative follow-up of lung cancer.

DISCLOSURE:  Yuichi Sakairi, Grant monies (from industry related sources) KY has received unrestricted grants from Olympus Medical Systems for continuing medical education.; No Product/Research Disclosure Information

Wednesday, November 4, 2009

12:45 PM - 2:00 PM


Figures

Tables

References

NOTE:
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).

Some tools below are only available to our subscribers or users with an online account.

Related Content

Customize your page view by dragging & repositioning the boxes below.

CHEST Journal Articles
PubMed Articles
  • CHEST Journal
    Print ISSN: 0012-3692
    Online ISSN: 1931-3543