The clinical characteristics of Central sleep apnea (CSA)are thought to be similar, but usually less severe, to those of patients with OSA but these characteristics have not been examined in a controlled fashion. Purpose of this study was to compare clinical and polysomnographic (PSG) data between CSA and OSA populations after matching for age, race and gender.
CSA was defined as central AH index ≥5/hr and OSA index ≤5/hr. Retrospectively we reviewed charts and PSG’s of all patients diagnosed with CSA in last 2 years (n = 38) and compared data with OSA patients selected to match (n = 38) for age (57 vs. 55), race (C 26/26, AA 12/12), and gender (M 31/31, F 7/7) from our data base.
Compared to OSA patients, CSA patients presented less commonly with snoring (23/38 vs. 32/38 P = .005), and witnessed apnea (19/38 vs. 27/38 P = .04). There was no difference in Epworth Sleepiness Scale (12 ± 5 vs. 12 ± 6 P = NS). BMI was similar in both groups (38 ± 36 vs. 37 ± 36 P = NS). A history of coronary artery disease (CAD) was more prevalent in CSA patients (18/38 vs. 6/38 P = .003). Review of PSG data revealed AH index was not different between CSA and OSA (27 + 20 vs. 24 + 20 P = NS). Periodic leg movements were more prevalent in CSA as compared to OSA (27 + 89 vs. 9 + 30 P = .027).
After controlling for age, race and gender a comparison of CSA and OSA patients revealed that CSA patients presented less commonly with a history of snoring and observed apneas, but more commonly had a history of CAD. CSA patients had a similar degree of day time sleepiness and obesity to matched OSA patients.
Evaluation of day time sleepiness with a PSG should be considered in obese patients with a history of CAD even in those without snoring or witnessed apneas.
I. Sharief, None.