In patients with tuberculous pleurisy, the residual pleural thickening(RPT) that produce symptoms like dyspnea and chest discomfort is the common sequelae after treatment of tuberculous pleurisy. But there are not known predictable factors and preventable methods for pleural thickening. We studied about the effects of tube drainage on RPT.
70 patients who treated with anti-tuberculous medication for at least 6 months, were included for study. We performed tube drainage that include chest tube and pig tail drainage, in 34 patients (group I) at a point of anti-tuberculous treatment. 36 patients (group II) treated only with anti-tuberculous treatment after diagnostic thoracentesis. In group I performed with tube drainage (n=34), we divided to two subgroups that are with initial loculation (group Ia, n=26) and without initial loculation (group Ib, n=8). In initial loculated pleural effusion (n=35), the tube drainage group is group A (n=26), and the no tube drainage group is group B (n=9). We used residual pleural thickness as average value of residual pleural thickening at the 3 points of lateral chest wall.
RPT in group I is larger than in group II (2.53±1.86mm vs 2.40±5.28mm), but it’s not statistically significant (p>0.05). RPT in initially loculated subgroup (group Ia) is significantly smaller than RPT in initially not-loculated subgroup (group Ib) (p<0.05). In initial loculated pleural effusion (n=35), RPT in tube drainage group (group A) is smaller than RPT in no tube drainage group (group B) (3.92±1.82mm vs 4.33±9.46mm), but it’s not statistically significant (p>0.05).
Tube drainage is helpful in reducing the RPT in initial loculated group than initial not-loculated group, statistically significant. Tube drainage can reduce theoretically pleural thickening as a sequelae of tuberculous pleurisy. As our results, tube drainage is helpful in reducing RPT only in patients with initial loculated pleural effusion rather than not-loculated effusion.
Tube drainage will be helpful in reducing RPT in especially loculated pleural effusion. We expect further large studies about factors related with residual pleural thickening in tuberculous pleurisy.
M.J. Na, None.