Analyze the initial hemodynamic behavior of the illness and determine if exist any data for differentiate this illness from others interstitial lungs diseases.
We reviewed the hemodynamic characteristic at rest as in exercise with right cardiac catheterization (RCC) of 20 patients with the diagnostic of EAA in a retrospective and observational study with statistical analysis of the hemodynamic of these patients.
From October of 1996 to June of 2002 we found 200 patients with interstitial diseases, 21 with diagnostic of EAA (10.5%). 20 patients were included in the study, 19 females and 1 man with a mean age of 51.5 ± 16.5, 18 had histological diagnostic by open lung biopsy the remaining two had clinic-tomography (One patient did not accept the procedure and one more was rejected for sever pulmonary hypertension). 60% of the 20 patients evaluated presented pulmonary hypertension (The mean pulmonary pressure was at rest 25.7 mmHg. ± 13.45) without significant increase during exercise (40.2 mmHg. ± 15.54 p=0.276). The mean pulmonary wedge pressure was 5.29 mmHg at rest and 7.61 mmHg in exercise without statistical significance.The mean cardiac index was 3.58 L/min./m2 at rest and 4.79 L/min./m2 in exercise with a p= 0.628 and 0.564 respectively (been significant with p ≤ 0.05). The were not hemodynamic findings that reached statistical significance but in the other hand the data of the blood gas exchange did it, like Qs/Qt%, PvCO2, PvO2, G a-vO2.
In Conclusion our study showed that even we found similar results in the hemodynamic at rest and exercise, there were only differences in the blood gas exchange and that theses differences were more significant in the venous blood gas exchange.
We hypothesized that the hemodynamic of the patient with EAA can be a determinant for differentiate it form others interstitial pneumopathies but the result showed the opposite. More hemodynamics studies are needed to better understand the illness and offer other therapies that render in the best life quality and expectancy.
E. Bringas, None.