To report a single center experience with ECLS for severe ARDS pathophysiology caused by pneumonitis.
ECLS (ECMO) supports cardiac and pulmonary function in the absence of native organ function allowing time for treatment of primary pulmonary disease. Between 1990 and 2003 we treated 132 moribund patients with ECLS. Patient characteristics AaDO2 612, shunt fraction 55%, P/F rtio 54, all despite and after optimal treatment (3.8 ventilator days). Average time on ECLS was 9 days. Septic shock and multiple-organ failure were common complications.
The cause of pneumonia, numbers of patients, and hospital discharge survival was: bacterial N79, 57%; viral N33, 55%; aspiration N13, 62%; fungal N7, 29%; overall cases N132, 55% survival.
Extracorporeal life support resulted in recovery and survival in 55% of 132 patients with overwhelming pneumonitis.
ECLS should be considered in patients with high mortality risk from pneumonitis.
R.H. Bartlett, None.