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Health Related Quality of Life(HRQL) Scoring in Tuberculosis FREE TO VIEW

Jorawar Singh, MBBS*; Nirmal C. Kajal, MD; Mohinder Singh, PhD; Vishal Verma, MBBS
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Medical College, Amritsar, India


Chest. 2004;126(4_MeetingAbstracts):833S-b-834S. doi:10.1378/chest.126.4_MeetingAbstracts.833S-b
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PURPOSE:  To evaluate the impairment of health related quality of life in tuberculosis patients during treatment at 0 week, 4 week & 8 week by HRQL questionnaire.

METHODS:  100 patients (15 years & older) put on treatment under RNTCP on DOTS categories at chest & TB Hospital Amritsar were included. All patients were subjected to pretested questionnaire used by Dhingra & Rajpal 2003. Questionnaire was based on symptoms (score I), Physiological, Psychological & social interaction of the patients (score II). Patients were asked to evaluate their symptoms on a scale of 1-3.

RESULTS:  : Data was analyzed after grouping the patients as DOT categories I, II, & III, in relation to site of disease (Pulmonary of extrapulmonary), sex and sputum status. It was observed that there was perceptible increase in the HRQL score at 4 week & 8 week in all categories of the patients as shown in table IDOTS CategoriesO week4 week8 weekI22.92 ±2.2328.10 ±1.3833.10 ±2.85II22.04 ± 4.9226.5 ± 5.7331.80 ± 7.10III22.61 ± 15.728.57 ± 1.7734.07 ± 1.71. It was also noticed that increase in HRQL score in case of patients, who did not convert sputum negative at end of intensive phase, was low as compared to those who turned sputum negative.

CONCLUSION:  HRQL score is useful in quantifying the overall health of the patients as perceived by him/her. This is evident from the results of the study. The HRQL scoring increased as the patients improved with treatment. Betterment was observed in all the areas i.e. psychological, physiological as well as social interaction. Improvement was observed in both the males & females patients with pulmonary or extrapulmonary disease. HRQL questionnaire did discriminate among patients not showing improvement as indicated by their sputum positivity for AFB even after 8 weeks of treatment.

CLINICAL IMPLICATIONS:  HRQL scoring in TB is useful as it provide hard data quantifying the health of the patient as perceived by the patients. However it has to be used with caution in individual patients and may not be taken as a substitute for observation made regarding clinical improvement.

DISCLOSURE:  J. Singh, None.

Wednesday, October 27, 2004

12:30 PM - 2:00 PM




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