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Abstract: Poster Presentations |

Early Lung Cancer Detection - A Comparison of Autofluorescence-bronchoscopy And Videochipbronchoscopy FREE TO VIEW

Felix J. Herth, MD*; Ralf Eberhardt, MD; Heinrich D. Becker, MD; Armin Ernst, MD
Author and Funding Information

Thoraxklinik, Heidelberg, Germany


Chest


Chest. 2004;126(4_MeetingAbstracts):819S. doi:10.1378/chest.126.4_MeetingAbstracts.819S
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Abstract

PURPOSE:  Autofluorescense bronchoscopy (AF) is an established method to detect dysplasia and carcinoma in situ. Videochipbronchoscopy (VC) is new development in this field. VC allows a computer-based analysis of the bronchial mucosa. This study aimes to directly compare the D-light system and videochiptechnology in detection of early lung cancer.

METHODS:  In a prospective study we examined patients with risk factors for lung cancer who underwent bronchoscopy with both methods. The findings were classified in normal, abnormal and suspicious lesions by independent investigators and compared.

RESULTS:  300 consecutive patients (208 male, 92 female, mean age 52,7 years, range (r) 40-85) were included. 21 patient had a class IV lesion, all detected by both systems. 17 (6%) pts had a histological controlled class III lesion (2x CIS, 8x servere dysplasia, 7x mild dysplasia). Thereof AF missed one mild dysplasia. 13 pts. showed with AF endoscopically a class III lesion, histological only inflammation. With VC 10 of this lesion were classified as class II lesions. The mean time for the both examination were similiar.

CONCLUSION:  Both system yielded comparable results. With VC the rate of false positive results is decreased compared to AF.

CLINICAL IMPLICATIONS:  Early lung cancer detection is also possible with the new videochiptechnology.

DISCLOSURE:  F.J. Herth, None.

Wednesday, October 27, 2004

12:30 PM - 2:00 PM


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