Abstract: Poster Presentations |

Incidence of Echocardiogrphic Lesions in Mixed Connective Tissue Disease FREE TO VIEW

Ioannis Moyssakis, FESC*; Dimitris P. Papadopoulos, Dr; Cristoforos Georgakopoulos; V. Vasiliou; Panagiotis Marcos; Vassilios Votteas, Asst. Prof
Author and Funding Information

Laiko Hospital, Athens, Greece


Chest. 2004;126(4_MeetingAbstracts):789S. doi:10.1378/chest.126.4_MeetingAbstracts.789S-c
Text Size: A A A
Published online


PURPOSE:  Mixed connective tissue disease (MCTD) is a syndrome with features of systemic lupus erythematosus, systemic sclerosis, polymyositis, and rheumatoid arthritis. High titers of circulating antibodies to nuclear ribonucleoprotein are frequently identified in affected patients (pts).

METHODS:  Forty seven ( 34 females-13 males, aged 53±12 years) pts with MCTD were evaluated with M-mode, 2D and Doppler echocardiography. Parameters measured included: Left ventricular (LV) dimensions and the peak velocity of the tricuspid regurgitant jet for the fractional shortening (FS) and pulmonary hypertension calculation respectively. Organic valvular involvement was defined as valve thickening and/or regurgitation.

RESULTS:  Depressed LV function (FS<29%) was present in 5 pts (10.6%) and was diffusely impaired. Valvular regurgitation was found in 6 pts (12,7%) and was mild mitral regurgitation (in two due to mitral valve prolapse). Pulmonary hypertension had 7 pts (15%), pericardial effusion 8 (17%) and LV hypertrophy 4 (8.5%) pts.

CONCLUSION:  In mixed connective tissue disease cardiac abnormalities are quite common with more frequent being pulmonary hypertension and pericardial effusion.

DISCLOSURE:  I. Moyssakis, None.

Wednesday, October 27, 2004

12:30 PM - 2:00 PM




Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).

Some tools below are only available to our subscribers or users with an online account.

Related Content

Customize your page view by dragging & repositioning the boxes below.

CHEST Journal Articles
PubMed Articles
  • CHEST Journal
    Print ISSN: 0012-3692
    Online ISSN: 1931-3543