Abstract: Poster Presentations |

Local Recurrence and Long-term Survival Following Curative Resection of Localized Fibrous Tumors of the Pleura FREE TO VIEW

Ricardo S. Santos, MD; Deepak Singh, MD; Yannis Raftopoulos, MD; Margareth Mizstal, MD; Yulin Liu, MD,; Jan Silverman, MD,; Robert Keenan, MD; Rodney Landreneau, MD
Author and Funding Information

Allegheny General Hospital, Pittsburgh, PA


Chest. 2003;124(4_MeetingAbstracts):233S. doi:10.1378/chest.124.4_MeetingAbstracts.233S-b
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PURPOSE:  Localized fibrous tumors of the pleura (LFTP) are rare, slow growing thoracic neoplasms with variable malignant potential. This study reviews the clinical presentation, surgical treatment, local recurrence and long-term survival of patients undergoing curative resection of LFTP in our department.

METHODS:  This is a retrospective chart review of 13 patients undergoing resection of LFTP. Tumors were classified as malignant, or benign based on degree of cellularity, mitotic activity and nuclear pleomorphism.

RESULTS:  There were 9 women and 4 men with a median age of 65 years (range 45-81 years). Four patients (30.8%) presented with symptoms including chest pain and weight loss (n=1), chest pain alone (n=2) and cough (n=1). Nine patients had no symptoms and the diagnosis was made based on incidental radiological findings. Tumor size ranged from 1.2 to 24 cm, with a mean of 7.2 cm. Two tumors were considered malignant and the remaining 11 were benign. Both patients with malignant LFTP recurred locally and required a total of 7 additional resections. One out of 11 tumors (9.1%), which was classified as benign also recurred and required 3 additional resections. All patients are alive at a median follow-up of 34.5 months.CONCLUSIONS: Malignant LFTP have a higher incidence of local recurrence compared to benign LFTP. Resection of recurrent tumors is recommended as long-term survival is excellent.

CLINICAL IMPLICATIONS:  LFTP is a rare pleural tumor, however, pulmonary phsisician should be aware as complete resection yield excellent survival.

DISCLOSURE:  R.S. Santos, None.

Wednesday, October 29, 2003

12:30 PM - 2:00 PM




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