The aim of this study is to investigate clinical characteristics, surgical treatment, and outcome of patients with the rare entity of solitary fibrous tumor of the pleura operated in our institution for 10 years.
Clinical records of all patients operated for solitary fibrous tumors of the pleura between 1994 and 2003 were reviewed retrospectively. All tumors were classified benign or malignant by the pathologic criteria of hypercellularity, high mitotic activity, or pleomorphism.
Twenty two patients (men 14, women 8) were operated in this period. Mean age was 51 years (range 25-83). None had history of asbestos exposure.Symptomatic patients were 13 cases (59%). Surgical approaches included thoracotomy (n=14) and video-assisted thoracic surgery (n=8). Mass excision at their base of pleural origin was possible in 11 cases. Extended resection was performed in 11 cases (lobectomy 1, pneumonectomy 10). In pleuropneumonectomy cases, extended resetions were performed in 7cases including diaphragm, chest wall, or pericardium. There was no operative mortality. Tumors were pathologically benign in 11 cases and malignant in 11 cases. Mean follow-up was 21 months (benign 31 months, malignant 9.7 months). Resection was complete in all benign and malignant cases. Recurrence or distant metastasis was observed only in malignant cases. Local recurrence was observed in 2 cases and 1 was managed by completion pleuropneumonectomy. Metastatic diseases were observed in 6 cases (bone 2, brain 2, lung 2).
Complete surgical resection was curative treatment fot benign solitary fibrous tumors of the pleura.CLINICAL IMPLICATION: Clinical and radiologic close follow-up should be emphasized after resection of malignant form of solitary fibrous tumors of the pleura.
J. Chang, None.