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Abstract: Poster Presentations |

Chronic Obstructive Pulmonary Disease (COPD): Evaluation of Familiar Antecedents as a Risk Factor and Its Relationship With Smoking Habit FREE TO VIEW

Abraham Zavala Battle, MD FCCP; Clinica Javier Prado
Chest. 2003;124(4_MeetingAbstracts):229S. doi:10.1378/chest.124.4_MeetingAbstracts.229S-a
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Abstract

INTRODUCTION:  Many years ago it has been established the near relationship between smoking habit and the development of COPD (chronic obstructive pulmonary disease), although we know that only 80% of COPD are produced by smoking and less than 20% of heavy smokers develop COPD. This take us to think that there are other risk factors for the development of COPD.

PURPOSE:  To determine if familiar antecedents for COPD are an important risk factor to develop COPD. To determine if hereditary predisposition associated to smoking habit increases the likelihood to develop COPD if compared with the mentioned risk factors separately.

METHODS:  This is descriptive, transversal cut type study that includes 116 people of both sex between 30 and 45 years old in whom we compare pulmonary function in smokers, non smokers, with and without family COPD antecedents. It’s considered positive the following measures: FV1/FVE< 70% or FEV1 < 80% without reversibility or with reversibility less than 12% with inhaled Beta-agonists. We consider patients with positive spirometry as an incipient COPD carrier.

RESULTS:  The results show that smokers with family COPD antecedents showed higher positive spirometry percentage (27.6%) followed by no smokers with family COPD antecedents (17.2%). The third group in positive spirometry percentage was the one with smokers with no family COPD antecedents (10.3%). The group with no smokers and no family COPD antecedents showed no positive spirometry. There was significative statistical difference between the four groups.CONCLUSIONS: We conclude that familiar antecedents for COPD are a significative risk factor to develop COPD. Familiar antecedents for COPD associated to smoking habit increase the likelihood to develop COPD if compared with the mentioned risk factor separately.

CLINICAL IMPLICATIONS:  To determine a risk group can help work hardly in prevention, diagnosis and early therapy.

DISCLOSURE:  A. Zavala Battle, None.

Wednesday, October 29, 2003

12:30 PM - 2:00 PM


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