We attempt to identify the physiological/clinical parameters which are relevant to the survival rate of the elderly patients who suffer from respiratory failure. This is helpful in targeting the patients who will most likely benefit from mechanical ventilators.
Subjects are patients over 80 who have been diagnosed with respiratory failure and received mechanical ventilation. Data on age, sex, diagnosis, medical history, functional/nutritional status and acute physiological parameters during the first 24 hours of admission to the intensive care units were collected. The analysis of data is done by chi-square tests of contingency tables.
55 patients, 34 females and 22 males, with a mean age of 86 and a survial rate of 42%: Patients who maintained a mean arterial pressure of more than 65 (p-value = 0.002) and did not need pressers (p-value = 0.005) with no developing acidosis (p-value = 0.023) showed a significant increase in the rate of survival. PaO2/FIO2% > 200 (p-value = .478) and albumin > 3 mg/dl (p-value = 0.211) did not seem to have a statistically significant impact on the survival of the subject. Functional status of a patient before respiratory failure (p-value = 0.486) and blood transfusion during hospitalization ((p-value = 0.484) did not appear to be significant factors either. However, the duration of mechanical ventilation less than 3 days was a significant factor for survival (p-value =0.01).
A low mean arterial pressure, the need for pressors and acidosis during the first 24 hours; and the duration of ventilation are the predictors of the favorable outcome (survival) in the elderly patients.
The elderly patients who fit the above profile most benefit from the ventilators.
J. Kaberi-Otarod, None.