The association of human immuno deficiency virus (hiv) infection and lung cancer remains unclear. This study analyzes the charecteristics of patients with lung cancer and hiv treated at our institution from 1991–2000.
Data regarding patients with hiv and lung cancer (study group) was obtained retrospecteivley from medical records. We also analyzed records of thiry six patients with lung cancer and unknown hiv status as a control group.
Median age of patients with hiv infection and lung cancer was 50.all patients were of african american ethnicity. Patients in the study group had a median survival of nine months compared to a median survival of seventeen months in the control group (p=0.12).study group had a higher proportion of patients with adenocarcinoma . Majority of patients in either group were smokers and presented with advanced stages of lung caner. All patients in the study group had non small cell lung cancer .CONCLUSIONS: Patients with hiv seropositiity and lung cancer were younger compared to patients with lung cancer in the us.the high proportion of african american patients in this study reflects the patient population seen at our institution.no significant differences in survival was noted in hiv seropositive patients with lung cancer compared to the control group. Further studies in a larger patient population is needed to clarify any survival differences.
This series of african american patients with hiv and lung cancer had clinical feartures similar to earlier reports in the literature. The study failed to show any significant differences in survival in patients with hiv infection and lung cancer compared to patients with lung cancer and undetermined hiv status. Patietns with hiv and lung cancer may benefit from aggressive treatment approaches since they do not appear to have a worse prognosis.
E.A. Nidhiry, None.