0
Abstract: Poster Presentations |

Inspiratory Capacity Is a Determinant of Exercise in Patients With Primary Dilated Cardiomiopathy FREE TO VIEW

Emilio Marangio, MD, FCCP; Claudia Castagnetti, MD; Raffaele D’Ippolito, MD; Antonio Castagnaro, MD; Marina Aiello, MD; Maria V. Tonna, MD; Antonio Foresi, MD; Dario Olivieri, MD, FCCP; Alfredo Chetta, MD, FCCP.
Author and Funding Information

University of Parma, Parma, Italy


Chest


Chest. 2003;124(4_MeetingAbstracts):186S. doi:10.1378/chest.124.4_MeetingAbstracts.186S-a
Text Size: A A A
Published online

Abstract

PURPOSE:  Inspiratory capacity (IC) can determine exercise capacity in patients with lung diseases. In this study, we investigated the role of IC in the exercise capacity of patients with cardiac diseases.

METHODS:  Twenty patients (4 female, age range 29-79 years, BMI range 16-30 kg/m2) with primary dilated cardiomyopathy (NYHA class range 1-3; mean±SD ejection fraction: 32%±11) performed spirometry and lung volumes measurement. Patients carried out exercise testing using bicycle ergometry with ramp protocol (work rate increments range 5-15 W/min). Gas exchange and ventilation were measured breath by breath.

RESULTS:  Mean(SD) values of IC, FEV1, FEV1/VC, and TLC were 2.88L(0.7), 93%pred(16), 76%(6), and 96%pred(15), respectively. At peak of exercise, mean(SD) values of V’O2, HR and Work Load were 1.39L(0.53), 137bpm(27), and 115watts(59). IC was related to NYHA class (rs=−0.49, p<0.05), V’O2 (r=0.75, p<0.01), and Work Load (r=0.79, p<0.01). Moreover, IC was chosen by multiple regression analysis, as the main predictor variable for V’O2 (r2 = 0.56).CONCLUSIONS AND CLINICAL IMPLICATIONS: In patients with primary dilated cardiomyopathy, resting inspiratory capacity is strictly related to exercise capacity and predicts the oxygen uptake at peak of exercise. Our data suggest that inspiratory capacity can be used in the clinical assessment of primary dilated cardiomyopathy.

DISCLOSURE:  A. Chetta, None.

Wednesday, October 29, 2003

12:30 PM - 2:00 PM


Figures

Tables

References

NOTE:
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).

Some tools below are only available to our subscribers or users with an online account.

Related Content

Customize your page view by dragging & repositioning the boxes below.

Find Similar Articles
CHEST Journal Articles
PubMed Articles
Guidelines
  • CHEST Journal
    Print ISSN: 0012-3692
    Online ISSN: 1931-3543