The aim of our study was to investigate and compare the left ventricular (LV) systolic and diastolic function in patients (pts) with idiopathic dilated cardiomyopathy (DCM) with biventricular systolic dysfunction versus pts with DCM without right ventricular (RV) systolic impairment.
Twenty two (14 males - 8 females, aged 57±11 years) pts with biventricular systolic dysfunction (group A) and 28 (19 males – 9 females, aged 55±13 years) pts with isolated LV impairment were recruited in the study. All pts underwent complete echocardiographic study. Parameters measured were LV dimensions for ejection fraction (EF) calculation, early and late transmitral flow velocities (E and A wave respectively). E/A ratio, deceleration time (DT) and isovolumic relaxation time (IVRT). We also evaluated LV Tei index and mitral annulus plane systolic excursion (MAPSE) whereas the RV systolic dysfunction was assessed by the tricuspid annulus plane systolic excursion (TAPSE) or RV dp/dt. Values of TAPSE equal to or less than 12.5 mm and RV dp/dt < 220 mmHg/sec were considered decreased.
See tableResults tableParametersGroup AGroup BP-ValueLVEF (%)28 ± 1035 ± 9<0.05MAPSE (mm)9.3 ± 0.910.2 ± 1.0<0.01LV Tei-index0.57 ± 0.140.49 ± 0.12<0.05LV E/A1.79 ± 0.321.66 ± 0.25<0.05LV DT (msec)150 ± 29164 ± 26NSLV IVRT(msec)66 ± 1271 ± 8NS.CONCLUSIONS: Our findings suggest that biventricular systolic dysfunction in DCM causes more severe impairment of systolic and diastolic function versus isolated LV involvement.
N.J. Pantazopoulos, None.