Abstract: Poster Presentations |

Bronchodilator-induced Decrease in Oxygen Saturation (02 Sat) in Patients With Obstructive Lung Disease FREE TO VIEW

A Al-Shrouf, MD; M Ismail, MD; G Wardeh, MD; S Momany, MD; M A. Khan, MD, FCCP
Author and Funding Information

St. Joseph’s Regional Medical Center, Paterson, NJ and Seton Hall University, School of Graduate Medical Education, S. Orange, NJ


Chest. 2003;124(4_MeetingAbstracts):171S. doi:10.1378/chest.124.4_MeetingAbstracts.171S-b
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PURPOSE:  Bronchodilator therapy affects ventilation-perfusion relationships in the lung. In order to asess whether such therapy may impair 02 Sat, we prospectively studied a group of 89 patients referred to our PFT laboratory for lung function studies.

METHODS:  Eighty-nine subjects (46 females, 43 males, age range:35-84 years; mean age:64 years) underwent pulse oximetry while performing pulmonary function studies before and during bronchodilator aerosol inhalation.

RESULTS:  Forty-nine patients (26 females, 23 males) were diagnosed with obstructive lung disease (FEV1/FVC<70) while 40 patients either had normal lung function or restrictive defect. Nine of 49 (18%) patients with obstructive lung disease showed a mean drop of 3% in 02 Sat while receiving bronchodilator aerosol. None of the patients with normal lung function or restrictive defect showed a drop in 02 Sat (P=0.010).

CONCLUSION:  Bronchodilator aerosol therapy resulted in 3 mm decrease in 02 Sat in 18% patients with obstructive lung disease.CLINICAL IMPLICATION: Patients with obstructive lung disease should receive oxygen while using bronchodilator aerosol therapy to prevent a drop in 02 Sat.

DISCLOSURE:  A. Al-Shrouf, None.

Wednesday, October 29, 2003

12:30 PM - 2:00 PM




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