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Abstract: Poster Presentations |

Severity of Coronary Artery Disease in Patients With and Without Peripheral Arterial Disease FREE TO VIEW

Rishi Sukhija, MD; Kiran Yalamanchili, MD; Wilbert S. Aronow, MD
Author and Funding Information

New York Medical College, Valhalla, NY


Chest


Chest. 2003;124(4_MeetingAbstracts):147S-b-148S. doi:10.1378/chest.124.4_MeetingAbstracts.147S-b
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Abstract

PURPOSE:  To investigate in patients with and without peripheral arterial disease (PAD) undergoing coronary angiography for suspected coronary artery disease (CAD) the prevalence of left main CAD, 3-vessel or 4-vessel CAD, and of obstructive CAD.

METHODS:  Coronary angiography for suspected CAD was performed in 279 patients, mean age 71 years, with documented PAD and in 218 patients, mean age 70 years, without PAD.

RESULTS:  Compared to patients without PAD, patients with PAD had a higher prevalence of current or ex-cigarette smoking (85% versus 62%, p<0.001), of hypertension (71% versus 61%, p<0.05), of diabetes mellitus (53% versus 17%, p<0.001), and of dylipidemia (73% versus 60%, p<0.005). Left main CAD was present in 49 of 279 patients (18%) with PAD and in 1 of 218 patients (<1%) without PAD, p<0.001. Three-vessel or 4-vessel CAD was present in 177 of 279 patients (63%) with PAD and in 25 of 218 patients (11%) without PAD, p<0.001. Obstructive CAD (>50% stenosis) was present in 273 of 279 patients (98%) with PAD versus 177 of 218 patients (81%) without PAD, p<0.001.CONCLUSIONS: In patients undergoing coronary angiography for suspected CAD, patients with PAD have a higher prevalence of left main CAD, of 3-vessel or 4-vessel CAD, and of obstructive CAD than patients without PAD.

CLINICAL IMPLICATIONS:  Patients with PAD have an increased severity of CAD than patients without PAD and should be treated more aggressively with risk factor modification and with coronary revascularization.

DISCLOSURE:  R. Sukhija, None.

Wednesday, October 29, 2003

12:30 PM - 2:00 PM


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