For patients undergoing lung resection, estimation of postoperative lung function utilizing chest X-ray planimetry (CXR-planimetry) may be as effective as more complicated radionuclide studies of pulmonary regional ventilation and perfusion (regional-V/Q).
We estimated postoperative FEV1 (ppo-FEV1) using CXR-planimetry and regional-V/Q for patients who had pulmonary function studies before and after lung resection between Jan 1, 2000 and Dec 31, 2002 at UT MD Anderson Cancer. The estimated values obtained by each method were compared with one another and with the actual values measured postoperatively. Pearson’s comparison and linear regression tests were used to analyze this data. Patients’ demographics, underlying diagnoses, and types of surgical interventions were also studied.
Twenty patients (M=14, F=6) with a mean age of 61 yr (range 39 to 73) were evaluated. Fourteen patients had non-small cell lung cancers, 4 had mesotheliomas, and 2 had lung metastases from extrathoracic cancers. Surgery consisted of pneumectomy in 6 patients, lobectomy in 9, bilobectomy in 3, and segmental resection in 2. There was a strong association between values of ppo-FEV1 estimated by CXR-planimetry test and by regional-V/Q (r=0.989, p=0.00001). Both methods were also equally effective for predicting postoperative FEV1. We found a significant strong association between the results of FEV1 measured postoperatively with those estimated preoperatively by CXR-planimetry (r=0.828, p=0.00004) and by regional-V/Q (r=0.828, p=0.000001).
Chest X-ray planimetry can be as effective as regional-V/Q for predicting postoperative lung function for patients undergoing lung resection.
Chest X-ray planimetry can be used as a simple and inexpensive alternative for preoperative estimation of pulmonary function after lung resection.
Y.M. Ersoy, None.