Little data are available regarding the prevalence and characteristics of REM-OSA.We describe the prevalence and characteristics of REM-OSA.
We conducted a retrospective review of polysomnograms of patients diagnosed with obstructive sleep apnea at the Cleveland Clinic Foundation between July 1, 2000 and June 30, 2001. REM-OSA was defined as: overall apnea-hypopnea index (AHI) >5, REM-AHI >5, non REM-AHI (NREM-AHI) <5. We determined the prevalence and characteristics of REM-OSA. Correlation of REM-OSA with age, sex, body-mass index (BMI), Beck depression inventory (BDI), and Epworth sleepiness scale (ESS) was performed.
1012 patients were diagnosed with OSA between July 1, 2000 and June 30, 2001. 104 patients satisfied our criteria for REM-OSA diagnosis (10.3%). The mean plus or minus standard deviation for the different characteristics were: age (47.6±13.4) years, BMI (33.3 ±7.8) Kg/m2, ESS (10.9±5.1), BDI (9.6±8.1), REM-AHI (28.8±15.2), NREM-AHI (3.2±1.3), AHI (7.4±2.2). The percentage of women in the REM-OSA group was 46.2 versus 27.9 in the OSA group (p value < 0.001). A weak correlation was found between REM-AHI and BMI (r= 0.4), but none was detected between REM-AHI and any of the other characteristics.CONCLUSIONS: REM-OSA represents a significant proportion of patients with OSA and appears to have a different gender predilection. It may represent a distinct subgroup with characteristics different from the ones established for OSA.
REM-OSA with its different gender predilection may be a distinct subgroup of OSA. This may have therapeutic implications (continuous positive airway pressure therapy versus REM-suppressant medications).
G.S. Juvelekian, None.