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Interactive Physiology and Grand Rounds: INTERACTIVE PHYSIOLOGY GRAND ROUNDS |

A 22-Year-Old Woman With Unexplained Dyspnea

Elan Hekier, MD; Jess Mandel, MD
Author and Funding Information

Affiliations: From the Division of Pulmonary and Critical Care Medicine, University of California, San Diego School of Medicine, La Jolla, CA.

Correspondence to: Elan Hekier, MD, University of California, San Diego School of Medicine, Department of Medicine, 200 West Arbor Dr, MC 8383, San Diego, CA 92103; e-mail: ehekier@ucsd.edu


Editor's note: In this series, interactive diagrams are an important part of each article and are referred to throughout. You can access these online at [http://www.chestjournal.org/content/136/3/867.full]. Included with the diagrams are “Show Me” videos, animated narrations that walk you through the main points of each diagram. The first time you access the online material, you may be asked to update your Web browser's Flash Player plugin; this will enable you to view the diagrams as intended. If you are not automatically prompted to update the plugin and you have any problems using the diagrams, you can download the latest version of the Flash Player by visiting http://www.adobe.com/go/getflash.

Reproduction of this article is prohibited without written permission from the American College of Chest Physicians (www.chestjournal.org/site/misc/reprints.xhtml).


© 2009 American College of Chest Physicians


Chest. 2009;136(3):867-876. doi:10.1378/chest.09-0369
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Extract

Unexplained dyspnea represents one of the common reasons for referral to a chest physician. The etiology can lie within multiple organ systems, and its evaluation requires a keen understanding of the underlying physiology. In this case presentation, we review one etiology of unexplained dyspnea and employ the “Interactive Physiology Grand Rounds” approach to address the basic physiologic mechanisms of this disease. We pay specific attention to the hemodynamic complications and complex relationships between right and left ventricular (LV) function that are at play in this disease, and use interactive diagrams to illustrate key concepts.

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