MaryAnn Foote has done an excellent job of presenting a guide to writing up research results for publication.1–4 She has taken sections of a typical clinical trials research report one at a time and shown how it is done, focusing on CHEST requirements. Other very useful guides to scientific writing have also been published.5–17 The brief dissertation that follows is similar but presents in one document all elements of a research paper that may be either basic or clinical. It is also intended to be broadly applicable beyond CHEST. It does not address a variety of important associated issues such as who should be on the author list and in what position, which journal to submit to, or which ethical/conflict-of-interest issues to confront. At the outset, it must be recognized that there are literally thousands of scientific journals in existence. Each has its own list of instructions for authors that may to some extent conflict with, and therefore trump, the stereotypical approach of what now follows.