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Editorials |

Drug-Resistant Tuberculosis: What Is To Be Done?

Neil W. Schluger, MD
Author and Funding Information

Neil W. Schluger, MD, Chief, Division of Pulmonary, Allergy, and Critical Care Medicine, Professor of Medicine, Epidemiology, and Environmental Health Sciences, Columbia University College of Physicians and Surgeons, PH-8 East, Room 101, 630 West 168th St, New York, NY 10032; e-mail: ns311@columbia.edu

Dr. Schluger is Chief, Division of Pulmonary, Allergy, and Critical Care Medicine, Professor of Medicine, Epidemiology and Environmental Health Sciences, Columbia University College of Physicians and Surgeons.


The author has reported to the ACCP that no significant conflicts of interest exist with any companies/organizations whose products or services may be discussed in this article.

Reproduction of this article is prohibited without written permission from the American College of Chest Physicians (www.chestjournal.org/site/misc/reprints.xhtml).


© 2009 American College of Chest Physicians


Chest. 2009;136(2):333-335. doi:10.1378/chest.09-0785
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Extract

The article by Velayati and colleagues1 in this issue of CHEST (see page 420) describes cases of extensively drug-resistant (XDR) tuberculosis (TB) in Iran. The authors describe a pattern of resistance that they term “total drug resistance” (or TDR) to signal resistance of Mycobacterium tuberculosis isolates to essentially all antibiotics known to have activity against mycobacteria. Their report highlights several issues that need to be urgently addressed if progress is to be made in containing and reversing the spread of severely multidrug-resistant (MDR)-TB.

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