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Editorials |

Improving the Standard of Care for Patients With Idiopathic Pulmonary Fibrosis Requires Participation in Clinical Trials

Ganesh Raghu, MD; the IPFnet
Author and Funding Information

Ganesh Raghu, MD, Professor of Medicine, University of Washington, Box 356166, Seattle, WA 98195; e-mail: graghu@u.washington.edu

Dr. Raghu is Professor of Medicine, University of Washington.


This work is sponsored by NIH grant U10 HL080509.

Reproduction of this article is prohibited without written permission from the American College of Chest Physicians (www.chestjournal.org/site/misc/reprints.xhtml).


© 2009 American College of Chest Physicians


Chest. 2009;136(2):330-333. doi:10.1378/chest.09-0848
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Extract

Idiopathic pulmonary fibrosis (IPF) is an irreversible, fatal lung disease. Although the etiology of IPF is unknown, it is currently believed to occur as a result of repeated insults to the lungs over a period of years in individuals with occult, genetically determined, predisposing factors. Symptoms leading to diagnosis typically manifest in patients > 50 years old. Following diagnosis of IPF by surgical lung biopsy, the median survival is 2.8 years.1 While lung transplantation may improve survival for some patients, this option is appropriate for only a minority of patients with this debilitating disease.

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