Biomedical images (diagnostic images in clinical medicine and analytical images in the basic sciences) differ from other figures in scientific publications because they do not summarize or organize data. Rather, they are the data. For this reason alone, they need to be documented well. In addition, because interpretations of these images can vary widely (sometimes notoriously so), accurate and complete documentation should be provided to support each interpretation. If key information is missing, interpretations may be incomplete, inaccurate, or simply wrong.